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Shepherd, on her Facebook page, had this to say: “It is a sad day when my opponent’s campaign has stooped to spreading outright lies about my family. I think North Denver deserves better. I think that running for political office should be about your vision for the future and trying to improve the lives of the people you represent. That is what I have done. My opponent’s campaign should be ashamed of their slander.”
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SIRT1-KO mice show spatial learning and memory impairment. A , Success of SIRT1-KO mice (n = 5; open circles) to find the escape box in the Barnes maze was lower than for WT mice (n = 6; *p < 0.001; filled circles). B , Latency to find the escape box significantly decreased in WT mice compared with SIRT1-KO (*p < 0.001). C, D , Number of total errors ( C ) and deviations from the first error ( D ) (*p < 0.001) were both higher in SIRT1-KO mice than WT mice. E, F , Search strategy of WT ( E ) and SIRT1-KO ( F ) mice (serial strategy, yellow; spatial strategy, green; random strategy, red). Data represent means ± SEM. Statistical significance values correspond to the differences between curves analyzed all over the acquisition phase. *p < 0.05, days with statistical significance.
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guegreen Digital Replica Edition ► 2008 (414) Trending: MIU MIU Newsletters Donate Our Most Popular Lists “This new facility underscores the commitment Heartland Bank has for the Denver market,” notes Kevin Marvin, Regional President of Heartland. “Our expanded presence and services will enable us to attract new customers, while we continue to provide our existing customers with the excellent customer service that has made Heartland’s Denver banking center among its fastest growing locations.”
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(D) Joe Neguse* GUERIN GREEN: 1 MATCH! Become a Member / Subscribe Guerin Green, the editor and publisher of the North Denver News and Cherry Creek News, has been masquerading as a “journalist” in order to justify the harassment of two people for posts made on Colorado Pols. Yesterday we posted the audio file of a threatening message left for the Polster Laughing Boy. If you missed it, here’s the message:
Cherry Creek News Embed Tweet Burst responses in field CA1 of hippocampal slices from SIRT1-KO and NeSTO mice. Two different protocols of TBS, followed by 40 min of test-pulse recording were used. A , 5 × 3 TBS, five bursts at 5 Hz (theta burst), each burst consisting of three pulses at 100 Hz. B , 10 × 10 TBS, 10 theta bursts, each burst consisting of 10 pulses at 100 Hz. The duration of each pulse within TBS was double that of the test pulse. For each burst response during LTP induction, the area under the curve was measured and each burst area was normalized to the first burst area. (The bottom panels of simulated responses were not scaled.) C, D SIRT1-KO (open circles) and WT (filled circles) burst responses elicited by 5 × 3 TBS ( C ) and 10 × 10 TBS ( D ). E, F , NeSTO (gray bars) and Nestin–Cre (black bars) burst responses elicited by 5 × 3 TBS ( E ) and 10 × 10 TBS ( F ) (p < 0.005, two-way ANOVA). Data represent mean ± SEM.
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