May 20, 2015 Denver Business Journal PRLeap is a press release distribution service Denver CO 80207 I didn't know she was so unpopular a... Sarit Polsky, MD
Second, this is a BLOG. Nothing more. It’s not a news site, and it’s not a campaign tool. We don’t endorse candidates or take positions. What DEFENSE does is NOTHING like what we do. There is no comparison.
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Pols wields neither that carrot nor that stick. Source: Overexpression of SIRT1 in hippocampus does not alter LTP or associative memory. A , Western blot shows ∼16-fold SIRT1 protein increase in hippocampus of NeSTO mice compared with control Nestin–Cre animals. The numbers below show SIRT1 levels relative to actin. B , I/O curve of field EPSP slope versus current input (microamperes) is shifted to the left in NeSTO mice (n = 14; gray circles) compared with Nestin–Cre (n = 10; black circles; p < 0.0001, two-way ANOVA), suggesting increased basal synaptic excitability. C , Paired-pulse facilitation reveals normal presynaptic events in NeSTO mice (n = 5 each genotype). D , Similar LTP was elicited by 5 × 3 and 10 × 10 TBS (EPSP slopes; n = 7 each genotype) in mice overexpressing wild-type or increased levels of SIRT1. E, F , Fear conditioning to context ( E ) or tone ( F ) in Nestin–Cre (n = 14) and NeSTO animals (n = 18) show similar associative learning capacities in both strains. Data represent means ± SEM.
Green Oaks Foreclosures Activity Green is a great counter-example to the current argument over whether or not bloggers are journalists and should receive press immunities. Reader: Blogger outed by Guerin Green attacks power grabs, defends recall target Nate Easley
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Shepherd, on her Facebook page, had this to say: “It is a sad day when my opponent’s campaign has stooped to spreading outright lies about my family. I think North Denver deserves better. I think that running for political office should be about your vision for the future and trying to improve the lives of the people you represent. That is what I have done. My opponent’s campaign should be ashamed of their slander.”
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Broken Clouds The greatest infusion of corporate cash ever, over $600,000 in 2011 has gone to three school board candidates from so-called “reform interests” that have long sought to privatize and charterize traditional public education. The largest donors are corporate, including oil industry CEO Henry Gordon, healthcare industry CEO Kent Thiry, financial executive Scott Reiman, and former oilman and GOP fundraiser, current University of Colorado president Bruce Benson. Gordon and Reiman are board members of the Alliance for Choice in Education, a promoter of private school vouchers. Corporate money added to cash from outside groups like Stand for Children has accounted for tens of thousands of dollars to their three picks as school “reformers” — Happy Haynes for at-large, Anne Rowe in District 1 and Jennifer Draper Carson in District 5. The three candidates also garnered endorsements from the heavily hedge-fund-backed Democrats for Reform.
In a startling report released today, National Safety Council research shows just 13 states and Washington, D.C., have implemented comprehensive, proven actions to eliminate opioid overdoses and help protect their residents. In Prescription Nation, a digest analyzing how states are… Continue Reading →
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SIRT1-KO mice show spatial learning and memory impairment. A , Success of SIRT1-KO mice (n = 5; open circles) to find the escape box in the Barnes maze was lower than for WT mice (n = 6; *p < 0.001; filled circles). B , Latency to find the escape box significantly decreased in WT mice compared with SIRT1-KO (*p < 0.001). C, D , Number of total errors ( C ) and deviations from the first error ( D ) (*p < 0.001) were both higher in SIRT1-KO mice than WT mice. E, F , Search strategy of WT ( E ) and SIRT1-KO ( F ) mice (serial strategy, yellow; spatial strategy, green; random strategy, red). Data represent means ± SEM. Statistical significance values correspond to the differences between curves analyzed all over the acquisition phase. *p < 0.05, days with statistical significance.
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