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- Beds | 3 Baths | 2571 Sq. Ft. 303-954-2465 Looking for some inspiration? Shop our stylists' selection Overexpression of SIRT1 in hippocampus does not alter LTP or associative memory. A , Western blot shows ∼16-fold SIRT1 protein increase in hippocampus of NeSTO mice compared with control Nestin–Cre animals. The numbers below show SIRT1 levels relative to actin. B , I/O curve of field EPSP slope versus current input (microamperes) is shifted to the left in NeSTO mice (n = 14; gray circles) compared with Nestin–Cre (n = 10; black circles; p < 0.0001, two-way ANOVA), suggesting increased basal synaptic excitability. C , Paired-pulse facilitation reveals normal presynaptic events in NeSTO mice (n = 5 each genotype). D , Similar LTP was elicited by 5 × 3 and 10 × 10 TBS (EPSP slopes; n = 7 each genotype) in mice overexpressing wild-type or increased levels of SIRT1. E, F , Fear conditioning to context ( E ) or tone ( F ) in Nestin–Cre (n = 14) and NeSTO animals (n = 18) show similar associative learning capacities in both strains. Data represent means ± SEM.
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A version of this article appeared in print on April 10, 2016, in the Printers Row section of the Chicago Tribune with the headline "A meditation on repetition - `Notes On' explores the artistic process - and, as a byproduct, the Chicago art scene" — Today's paper | Subscribe
1995-96 NJ 80 0 - 0:00 0:00 - 0:00 0:00 0:00 0:00 0:00 0:00 SW Denver/Lakewood Prior to joining GBA, Cassie was a project coordinator at Ethos Collaborative, where she gained a variety of skills including grant writing, project proposal composition, research analysis, and relationship management. She also worked at the Environmental Charter School and an elementary school in Australia, overseeing a program that had students gardening in the farm and cooking meals using produce from the garden. During her spare time, Cassie likes to spend time in Frick Park, start conversations with strangers, and practice morning meditations (she’s a certified kundalini yoga instructor).
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New York Jets Polyester About Guerin Green This isn't about the Senate primary. If it was, I never would have publicly defended Andrea Merida against the recall attempt on her last fall. This is about exactly what I wrote.
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Reply DELVAUX © Twitter Neuronal dendritic trees from SIRT1-KO mice show less branching and complexity than WT mice. A , Sholl analysis shows significantly less dendritic material over the entire neuronal tree in SIRT1-KO mice; p < 0.0001. B , Dendritic branch length was 22% lower in SIRT1-KO (100 ± 5.1%) than WT mice (122 ± 10%; p < 0.05). C , Neuronal dendritic arbors show less complexity in SIRT-KO mice (p < 0.05). SIRT1-KO and WT for all analysis correspond to n = 4 brain and n = 20 neurons (5 neurons per brain). Data represent mean ± SEM. Statistical significance values correspond to the differences between curves analyzed over the entire neuronal trees. Asterisks show the shells from the soma with statistical significance of p < 0.05.
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