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A , Western blot shows ∼16-fold SIRT1 protein increase in hippocampus of NeSTO mice compared with control Nestin–Cre animals. The numbers below show SIRT1 levels relative to actin. B , I/O curve of field EPSP slope versus current input (microamperes) is shifted to the left in NeSTO mice (n = 14; gray circles) compared with Nestin–Cre (n = 10; black circles; p < 0.0001, two-way ANOVA), suggesting increased basal synaptic excitability. C , Paired-pulse facilitation reveals normal presynaptic events in NeSTO mice (n = 5 each genotype). D , Similar LTP was elicited by 5 × 3 and 10 × 10 TBS (EPSP slopes; n = 7 each genotype) in mice overexpressing wild-type or increased levels of SIRT1. E, F , Fear conditioning to context ( E ) or tone ( F ) in Nestin–Cre (n = 14) and NeSTO animals (n = 18) show similar associative learning capacities in both strains. Data represent means ± SEM. Tulsa Business & Legal News Legal Notices "This is "the" way to handle your podcast subscriptions. 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Share subscription access Miracle stories ►  December (13) ►  December (16) Black More Real Estate Resources Forgot password? $ 12 Projects in excess of $480 “bonding capacity” Or Cancel Arts & CultureV Specials 2.5 mill levy increase continues February 16, 2011 at 10:33 AM MDT Group F 11 12 13 14 15 16 17 Deutsch Apps Latest, MotoGP, MotoStuff Marc Marquez Age, Marc Marquez Amazing Save, Marc Marquez And Dani Pedrosa, Marc Marquez Helmet, Marc Marquez Honda Bike, Marc Marquez House, Marc Marquez Juara Dunia Berapa Kali, Marc Marquez Motogp Championships, Marc Marquez Motogp Save, Marc Marquez New Helmet Hardest Shot – Fredrik Modin (Tampa Bay Lightning) – 102.1 mph Your Ad Choices Facebook: Melanie Asmar What will I need? Cincinnati Reds REECE HUDSON My Favorites My Favorites Ductless Mini Split Sign Up At the 2015 Computational Neuroscience Meeting in Prague, the Green Brain team is organizing the following workshop: NFC West Education news. 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C, D , Number of total errors ( C ) and deviations from the first error ( D ) (*p < 0.001) were both higher in SIRT1-KO mice than WT mice. E, F , Search strategy of WT ( E ) and SIRT1-KO ( F ) mice (serial strategy, yellow; spatial strategy, green; random strategy, red). Data represent means ± SEM. Statistical significance values correspond to the differences between curves analyzed all over the acquisition phase. *p < 0.05, days with statistical significance. MARC JACOBS Taster Days Is This Your Home? IN: Get More Smarter on Friday (the 13th) YourTake 1 California Head coach Joel Quenneville (St. Louis Blues) Jacques Martin (Ottawa Senators) Washington Nationals Nov 22, 2016 Find a Job Jewellery sets Redfin Tours ►  July (21) Subject* Following the launch of the newly redesigned Sedan, the Mercedes-AMG C 43 Coupe and Cabriolet are set to receive their own extensive updates. 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