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Green, who has two children in DPS neighborhood and magnet programs, is a longtime critic of DPS Superintendent Tom Boasberg and his predecessor Michael Bennet. More recently, he has taken aim at Seawell, posting Sunday on the No on Denver 3B Facebook page that she has become “the etch-a-sketch, say anything Mitt Romney of Denver politics … the worst of politics in a smiling, patronizing package.”
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Aurora Sentinel Latest IM news But Merida denied any involvement in maryseawell.com, stopdpsdebtnow.com or the two emails sent to DPS staff and others.
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Overexpression of SIRT1 in hippocampus does not alter LTP or associative memory. A , Western blot shows ∼16-fold SIRT1 protein increase in hippocampus of NeSTO mice compared with control Nestin–Cre animals. The numbers below show SIRT1 levels relative to actin. B , I/O curve of field EPSP slope versus current input (microamperes) is shifted to the left in NeSTO mice (n = 14; gray circles) compared with Nestin–Cre (n = 10; black circles; p < 0.0001, two-way ANOVA), suggesting increased basal synaptic excitability. C , Paired-pulse facilitation reveals normal presynaptic events in NeSTO mice (n = 5 each genotype). D , Similar LTP was elicited by 5 × 3 and 10 × 10 TBS (EPSP slopes; n = 7 each genotype) in mice overexpressing wild-type or increased levels of SIRT1. E, F , Fear conditioning to context ( E ) or tone ( F ) in Nestin–Cre (n = 14) and NeSTO animals (n = 18) show similar associative learning capacities in both strains. Data represent means ± SEM.
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