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Volume February 16, 2011 at 8:18 AM MDT The lack of SIRT1 does not affect exploratory behavior but leads to deficits in immediate memory. A, B , SIRT1-KO mice showed normal exploratory behavior in the open field compared with WT as revealed by distance traveled ( A ) and time spent in the center of the arena ( B ) (n = 4 per genotype; WT, 3.6 ± 1. 05%; KO, 3.4 ± 1.5%). C , Novel object recognition test shows normal discriminatory ability to a novel object in SIRT1-KO mice (n = 4 per genotype; training WT, 7 ± 5; training KO, 12 ± 6; test WT, 30 ± 12; KO test, 40 ± 13; p > 0.5). D , Decreased spontaneous alternation in the Y maze compared with WT mice (n = 16 per genotype; WT 58 ± 4 vs KO 48 ± 2%; *p < 0.05). Data represent means ± SEM. E , Cross sections of retinas from SIRT1-KO and WT mice show normal morphology of all retinal layers (ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer) by hematoxylin and eosin staining as well as by isolectin (red), GFAP (green), and DAPI (blue) staining ( F ). Scale bars, 100 μM.
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Center for Public Integrity Friday, the political blog site ColoradoPols.com was the first to link Green to the fake Seawell website. The post also describes Green as an “ally” of DPS board member Andrea Merida, who also opposes the DPS bond measure.
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More From: It’s always nice to have a positive opinion of someone and then find out they’re a fellow animal person. Thanks for the warm welcome over the months I’ve been commenting here. The outing thing has me rattled, but overall Pols has been such a friendly place, HMan and Beej notwithstanding.
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