Sarit Polsky, MD Rep. Mike Coffman 1.2 mi. ►  September (3) News Stroebe, W. (2012). The truth about triplett (1898), but nobody seems to care. Perspect. Psychol. Sci. 7, 54–57. doi: 10.1177/1745691611427306 (367) 20 Years of Living Healthy and Changing Lives - YouTube *Correspondence: Martine Meunier, martine.meunier@inserm.fr; fitness Speaker: Jean-Marc Devaud, Universite Paul Sabatier Lack of SIRT1 decreases hippocampal synaptic plasticity. A , I/O plots of field EPSP slopes versus current input (microamperes) were similar in WT (n = 7; filled circles) and SIRT1-KO (n = 8; open circles) mice, indicating that lack of SIRT1 does not alter baseline synaptic transmission. B , Paired-pulse facilitation (n = 3 each genotype) shows similar presynaptic plasticity in WT and SIRT1-KO mice. C , LTP in hippocampal CA1 field elicited by 5 × 3 and 10 × 10 TBS (EPSP slopes; WT, n = 5, filled circles; SIRT1-KO mice, n = 7, open circles). Five burst of 3 × 100 Hz stimulation evokes LTP in both genotypes, whereas 10 bursts of 10 × 100 Hz trains stimulation leads to a long-lasting form of LTP in control but not in SIRTI-KO mouse. D , EPSP slopes averages during the first 2 min after TBS (short-term potentiation) were similar in both genotypes. E , EPSP slopes averages 30–40 min after applying the 10 × 10 TBS protocol show significant differences in LTP induction in WT animals compared with SIRT1-KO mice (*p < 0.05, t test). Data represent means ± SEM. 2002-03 DAL 64 229 3.6 10.9% 0 0 - wpprofile@qwestoffice.net Trousers Guerin (Weight) 11:22 1st Journals A-Z WHY CHOOSE US Georgetown University Photography 299 Concord Sq Gurnee, IL 60031 Visit Website What if radio played only the shows you care about, when you want? Player FM is scanning the web for high-quality podcast content right now. Try us out on any web browser — desktop, mobile, or tablet. 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I need to get back to the paintings" — is invaluable for what it shows about the often unseen support systems necessary for an individual artist to function. Speaker: Andrew Barron, Macquarie University Staff Picks vooPlayer August 2, 2015 Feedback Wet multiplate anti-patter servo clutch Montreal Canadiens Thursday, November 10, 2016 © 2018 All rights reserved Samsonov (Forsberg, Lidstrom) 8:08 2nd "From my old Treo, to my Blackberry, to this new iPhone, I had a hard time hitting the right buttons, and I always lost those little styluses," Martel was quoted as saying. "Sure, the procedure was expensive, but when I think of all the time I save by being able to use modern handhelds so much faster, I really think the surgery will pay for itself in ten to fifteen years." From Wikipedia, the free encyclopedia 60 Views · View Upvoters Jimmie Tramel (30%)↑ SIRT1-KO mice show spatial learning and memory impairment. A , Success of SIRT1-KO mice (n = 5; open circles) to find the escape box in the Barnes maze was lower than for WT mice (n = 6; *p < 0.001; filled circles). B , Latency to find the escape box significantly decreased in WT mice compared with SIRT1-KO (*p < 0.001). C, D , Number of total errors ( C ) and deviations from the first error ( D ) (*p < 0.001) were both higher in SIRT1-KO mice than WT mice. E, F , Search strategy of WT ( E ) and SIRT1-KO ( F ) mice (serial strategy, yellow; spatial strategy, green; random strategy, red). Data represent means ± SEM. Statistical significance values correspond to the differences between curves analyzed all over the acquisition phase. *p < 0.05, days with statistical significance. 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